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Viral Vector Purification

Innovative synthetic affinity ligands for capture chromatography

High quality biological affinity ligands for capture chromatography of viral vectors are rare, if available at all. Smart polymers have the potential to transform the bioprocessing landscape by enabling efficient capture chromatography with delicate recovery.

Why choose smart polymers?

Designed in silico.

  • Our pioneering computational chemistry means we can screen the full surface of any viral particle, engineered or not, to identify optimally exposed epitopes and produce synthetic affinity reagents that are truly novel.
  • We have access to over 600 monomer building blocks (versus the traditional 20 amino acids) allowing us to build-in the exact functionality needed for the application.

Synthesized chemically.

  • The chemical manufacturing process of smart polymers means we can deliver a new wave of synthetic affinity reagents that go beyond the capabilities of biologics, providing safe, reproducible and scalable affinity solutions to our clients.
  • Smart polymers are free of Animal Derived Components (ADCs), reducing the risk of leached ligands on product quality and safety.
  • Robust purification formats allow for sterilization, increased cleanability and re-use potential.

Deployed with confidence.

  • Smart polymers offer new solutions to solving high value bioprocessing challenges for our clients. We are using our technology to go beyond what is currently possible.
  • Large batch sizes, rapid scale up and manufacturing consistency means clients can depend on the smart polymer supply chain.

Want to learn more?

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NEWS

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Research

Novel synthetic affinity reagents for lentivirus analytics and…

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