Who We are
Engineering a new generation of bioprocessing
Tozaro is transforming bioprocessing with a new class of synthetic affinity technologies. Our proprietary Smart Polymer™ technology combines computational modelling, machine learning and chemical synthesis to create purpose-built affinity ligands for purification and analytical applications.
By moving beyond traditional biologically derived affinity ligands, we are enabling faster development, cost-effective scalable manufacturing and tailored binding performance.
The Smart Polymer™ Platform
Tozaro’s Smart Polymer™ Platform is a proprietary technology that enables the rapid design and development of synthetic affinity ligands.
Using advanced computational modelling, we identify optimal binding regions on target molecules before screening billions of potential polymer combinations in silico, refined using machine learning. The most promising candidates are then synthesised in our labs and experimentally validated, significantly reducing development time while allowing binding characteristics to be engineered for specific chromatography applications.
Unlike conventional affinity ligands, Smart Polymers™ are chemically synthesised rather than biologically produced, providing a scalable, cost effective and flexible route to manufacturing while offering the potential to improve performance, reduce costs and strengthen supply chain resilience.
Development Pipeline
Our first generation of Smart Polymer™ products focus on viral vector purification and analytics, supporting the rapidly growing cell and gene therapy market.
| Target | Format | in silico design | ML Optimization | Development Chemistry | Imobilization Optimization | Chromatography Proof of Concept | Beta testing at Scale | |
|---|---|---|---|---|---|---|---|---|
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Lentiviral Vectors
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VSV-G LVV | Membrane |
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| VSV-G LVV | Monolith |
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| in vivo LVV pseudotype | Multiple |
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| in vivo LVV pseudotype | Rapid Analytics Platform |
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AAV
|
pan AAV | Membrane |
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| pan AAV | Monolith |
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| pan AAV | Resin / bead |
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| custom AAV capsid | Multiple |
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Biologics
|
undisclosed protein | Resin / bead |
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| Ab fragment | Resin / bead |
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Our Vision
A future where advanced manufacturing technology reduces the cost of curative cell & gene therapies, widening access to all.
Our Mission
To commercialise Smart Polymer reagents to increase purity and yield of advanced therapies while also simplifying downstream manufacturing processes.
Our Values
We innovate with purpose
Our focus is to drive innovation to impact real world processes and to deliver higher purity and lower cost
per dose, so more people benefit from innovative treatments.
We collaborate to understand, learn & improve
Open collaboration allows us to rapidly evolve through sharing ideas and combining knowledge
to generate high value reagents for advanced therapies.
We deliver excellence
We are committed to innovation, partnership and quality, helping our partners to be more successful
in all that they do.