Viral Vector Analytics
We are designing novel synthetic affinity reagents so you can deliver faster assays with greater insights
Tozaro is committed to overcoming the current compromise between speed, throughput, accuracy and cost when analyzing viral vectors. As critical components for most cell and gene therapies, we believe simple, fast and accurate analytics can be achieved with rationally designed affinity reagents at the core of new analytical platforms.
Smart polymers to power a new wave of analytical platforms
Current methods provide quick and useful indicators but are well known for overestimating the amount of virus present, and face challenges in complex sample compositions. We are operating at the intersection of chemistry and biology to design synthetic affinity reagents that bind exposed surface epitopes and easily integrate into our client’s technology and processes.
Tozaro is designing synthetic affinity reagents for the next generation of viral vector analytics.
Accurate Lentivirus titer
BETA EVALUATION
Tozaro has developed a suite of synthetic affinity reagents targeting VSV-G, a common lentivirus membrane protein. Designed to overcome overestimation seen when targeting other surface proteins, these new smart polymers will enable the development of fast and cost-effective lentivirus titrer assays with improved accuracy. Already demonstrated in an Octet BLI device, these smart polymers are now available for beta testing.
Why choose smart polymers?
Designed in silico.
- Our pioneering computational chemistry means we can screen the full virus surface to identify optimally exposed epitopes and produce affinity reagents that are truly novel.
- We have access to over 600 monomer building blocks (versus the traditional 20 amino acids) allowing us to build-in the exact functionality needed for the application.
Synthesized chemically.
- The chemical manufacturing process of smart polymers means we can deliver a new wave of synthetic affinity reagents that go beyond the capabilities of biologics, providing safe, reproducible and scalable affinity solutions to our clients.
- Smart polymers are free of Animal Derived Components (ADCs).
Deployed with confidence.
- Smart polymers offer fresh solutions to solving high value bioprocessing challenges for our clients. We are using our technology to go beyond what is currently possible.
- Large batch sizes, rapid scale up and manufacturing consistency means clients can depend on the smart polymer supply chain.
